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Conserving tropical biodiversity via market forces and spatial targeting

Protected public lands are insufficient to halt the loss of global biodiversity. However, most commercial landowners need incentives to engage in conservation. Through an interdisciplinary study examining

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Public health impacts of ecosystem change in the Brazilian Amazon

Nature threads the very fabric of human lives in remote forest areas of developing countries. Unfortunately, we do not fully understand how ecosystem services (such as human health benefits) could be...

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New approaches narrow global species estimates for beetles, insects, and...

Many suggest we are approaching a sixth mass extinction event, and yet estimates of how many species exist, and thus how many might become extinct, vary by as much as an order of magnitude. There are few

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Modeling malaria genomics reveals transmission decline and rebound in Senegal

Traditional methods for estimating malaria transmission based on mosquito sampling are not standardized and are unavailable in many countries in sub-Saharan Africa. Such studies are especially difficult

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Imperfect drug penetration leads to spatial monotherapy and rapid evolution...

The evolution of drug resistance is a major health threat. In chronic infections with rapidly mutating pathogens—including HIV, tuberculosis, and hepatitis B and C viruses—multidrug resistance can cause

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Rodent reservoirs of future zoonotic diseases

The increasing frequency of zoonotic disease events underscores a need to develop forecasting tools toward a more preemptive approach to outbreak investigation. We apply machine learning to data...

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Evaluating taboo trade-offs in ecosystems services and human well-being

Environmental management inevitably involves trade-offs among different objectives, values, and stakeholders. Most evaluations of such trade-offs involve monetary valuation or calculation of aggregate

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DDT-based indoor residual spraying suboptimal for visceral leishmaniasis...

Indoor residual spraying (IRS) is used to control visceral leishmaniasis (VL) in India, but it is poorly quality assured. Quality assurance was performed in eight VL endemic districts in Bihar State,...

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Pre- and postexposure efficacy of fully human antibodies against Spike...

Traditional approaches for development of antibodies are poorly suited to combating the emergence of novel pathogens, as they require multiple steps of laborious optimization and process adaptation for

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Impact of fossil fuel emissions on atmospheric radiocarbon and various...

A wide array of scientific disciplines and industries use radiocarbon analyses; for example, it is used in dating of archaeological specimens and in forensic identification of human and wildlife tissues,

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Systematic review of current efforts to quantify the impacts of climate...

Malnutrition is a challenge to the health and productivity of populations and is viewed as one of the five largest adverse health impacts of climate change. Nonetheless, systematic evidence quantifying

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An inhibitor persistently decreased enteric methane emission from dairy cows...

Methane from enteric fermentation in the ruminant digestive system is a major contributor to anthropogenic greenhouse gas emissions in the United States and worldwide. Methane is also a net loss of

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Threat of plastic pollution to seabirds is global, pervasive, and increasing

Plastic pollution in the ocean is a rapidly emerging global environmental concern, with high concentrations (up to 580,000 pieces per km2) and a global distribution, driven by exponentially increasing

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Fog and rain in the Amazon

We here demonstrate that we can resolve the seasonality of the hydrologic cycle in the Amazon using an approach, opposite to general circulation models, in which we resolve convection and parameterize

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Adaptive evolution of malaria parasites in French Guiana: Reversal of...

This study addresses the evolutionary dynamics of antimalarial drug resistance after changes in drug use. We show that chloroquine resistance in Plasmodium falciparum from French Guiana was lost after

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Synthesis of phylogeny and taxonomy into a comprehensive tree of life

Scientists have used gene sequences and morphological data to construct tens of thousands of evolutionary trees that describe the evolutionary history of animals, plants, and microbes. This study is

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No barrier to emergence of bathyal king crabs on the Antarctic shelf

For tens of millions of years, cold conditions have excluded shell-crushing fish and crustaceans from the continental shelf surrounding Antarctica. Rapid warming is now allowing predatory crustaceans to

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Global nutrient transport in a world of giants

The past was a world of giants, with abundant whales in the sea and large animals roaming the land. However, that world came to an end following massive late-Quaternary megafauna extinctions on land

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Highly efficient Cas9-mediated gene drive for population modification of the...

Malaria continues to impose enormous health and economic burdens on the developing world. Novel technologies proposed to reduce the impact of the disease include the introgression of parasite-resistance

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Inequality, climate impacts on the future poor, and carbon prices

Hundreds of published papers produce “optimal” trajectories of global emissions of carbon dioxide, and corresponding carbon prices, over this century, taking into account future damages

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